DATABASE
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Hormonal ● Verified

CJC-1295 (No DAC)

Mod GRF 1-29. GHRH analogue used synergistically with Ipamorelin for natural GH pulses.
Half-Life
~30 mins
Onset
Quickly
Duration
~2-3 hours
Route
Injectable
Mechanism of Action

Growth Hormone Releasing Hormone (GHRH) analogue. It binds to the GHRH receptor in the pituitary, amplifying the natural signal for GH release.

Key Benefits
  • Powerful synergy with Ipamorelin
  • Natural GH pulses (does not suppress own production)
  • Improved skin and body composition
  • Accelerated recoveryPowerful energy with Ipamorelin
  • Accelerated recovery
Evidence Notes
RESEARCH RANGE (Non-prescriptive): 100mcg per dose, usually combined with Ipamorelin. Level of Evidence: B.
Risk Profile
  • Flushing (heat in the face), mild palpitations.
Overview

CJC-1295 No DAC, also known as Mod GRF 1-29, is a short-acting GHRH mimetic peptide designed to simulate the natural physiological pulsations of growth hormone.

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What it is (in plain language)
- Unlike the DAC version, this peptide enters and leaves the system quickly. It doesn't force the body to produce GH all the time; instead, it increases the 'amplitude' of the beats your body already makes naturally, being much more respectful of the biological rhythm.

Why do you appear online so much
- It's considered the gold standard for those looking for safety. It is almost always combined with Ipamorelin to create a powerful but short GH pulse, ideal for administration before bed or after training.

How it is framed today (pragmatic view)
- 1) Evidence: Widely studied and considered very safe as it does not drastically interfere with the hormonal axis. 2) Objective: Muscle recovery and improved sleep quality. 3) Risk: Very low, mainly focused on the correct synchronisation of doses.

How to use this form
- See the 'Mod GRF vs DAC' section to decide which strategy best suits your biohacking profile.

- Quick profile (curated by Subject 157)
- Class: Hormonal
- Status: Verified
- Use case: Hormonal
- Route: Injectable
- Tags: Injectable|GH|Stack
- Half-life: ~30 Mins
- Start: Fast
- Duration: ~2-3 hours

- Mechanism (high level)
Growth Hormone Releasing Hormone (GHRH) analogue. It binds to the GHRH receptor in the pituitary, amplifying the natural signal for GH release.

- Evidence (what the literature covers)
RESEARCH RANGE (Non-prescriptive):
100mcg per dose, usually combined with Ipamorelin.
Level of Evidence: B.

- Safety and harm-reduction (non-prescriptive)
Risks: Flushing (heat in the face), mild palpitations.
Interactions: Unknown.

- References (anchors)
- Teichman, S. (2006) - CJC-1295 increases GH and IGF-I - https://doi.org/10.1210/jc.2005-1536 | PubMed:16330456
- Ionescu, M. (2006) - GH pulsatility during CJC-1295 - https://doi.org/10.1210/jc.2006-1702 | PubMed:17099145

Note: Educational/research content. Does not constitute medical advice, diagnosis or prescription.

Scientific References
Teichman, S. (2006) - CJC-1295 increases GH and IGF-I -
Ionescu, M. (2006) - GH pulsatility during CJC-1295 -
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Snapshot
Use CaseHormonal
AliasesMod GRF 1-29
StorageRefrigerator (2-8°C).
HandlingFragile.
Interactions
Unknown.
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