Epitalon

What it is (in plain language)
- It's the 'longevity peptide'. It acts directly on telomeres (the ends of our DNA that shorten as we age). By activating telomerase, Epitalon helps keep cells 'young' for longer and restores the functioning of the pineal gland, the body's master clock.

Why do you appear online so much
- It is the cornerstone of almost all life extension protocols. It was made famous by Professor Khavinson's studies, which showed significant reductions in mortality and improvements in general health in the elderly during long-term follow-ups.

How it is framed today (pragmatic view)
- 1) Evidence: Very promising long-term data in humans (Russian studies). 2) Purpose: Systemic longevity and circadian hormonal regulation. 3) Risk: Very high safety profile, no known toxic side effects at therapeutic doses.

How to use this form
- See the 'Khavinson Protocols' section to understand the recommended annual cycles.

- Quick profile (curated by Subject 157)
- Class: Other
- Status: Verified
- Use case: Other
- Route: Injectable
- Tags: Injectable|Longevity|Sleep
- Half-life: Unknown
- Start: Fast
- Duration: Variable

- Mechanism (high level)
Synthetic tetrapeptide (Ala-Glu-Asp-Gly). Induces telomerase activity (telomere extension) and regulates melatonin secretion via the pineal gland.

- Evidence (what the literature covers)
RESEARCH RANGE (Russian, Non-prescriptive):
Courses of 10mg daily for 10 days (Khavinson Protocol).
Level of Evidence: B (Longitudinal studies in Russia).

- Safety and harm-reduction (non-prescriptive)
Risks: None reported.
Interactions: Unknown.

- References (anchors)
- Khavinson, V. (2003) - Epitalon induces telomerase activity - https://doi.org/10.1023/a:1025493705728 | PubMed:12937682
- Anisimov, V. (2003) - Epitalon and lifespan biomarkers (SHR) - https://doi.org/10.1023/a:1025114230714 | PubMed:12739322

Note: Educational/research content. Does not constitute medical advice, diagnosis or prescription.