DATABASE
SYS.ONLINE
🔒 SECURE
Other ● Verified

GHK-Cu

Natural copper peptide, famous for its cosmetic properties and collagen regeneration.
Half-Life
~1 Hour
Onset
Slow (Skin)
Duration
Variable
Route
Topical
Mechanism of Action

Tripeptide with a high affinity for copper (Cu2+). Modulates gene expression (genetic reset), increases collagen/elastin and repairs DNA damage.

Key Benefits
  • Improved skin elasticity and reduction of wrinkles
  • Hair growth stimulation
  • Wound healing
  • Antioxidant and anti-inflammatory actionImproves skin elasticity and reduces wrinkles
  • Antioxidant and anti-inflammatory action
Evidence Notes
RESEARCH RANGE (Cosmetic/Injectable, Non-prescriptive): Topical (1-3%). Injectable (low doses, beware of copper toxicity). Level of Evidence: A (Cosmetic).
Risk Profile
  • Local pain on injection.
  • Accumulation of copper (monitor ZInco).Local pain on injection.
  • Copper accumulation (monitor ZInco).
Overview

GHK-Cu is a natural copper-peptide complex with pleiotropic properties, including tissue remodelling, DNA repair and modulation of the genetic expression of thousands of human genes.

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What it is (in plain language)
- It's the 'multivitamin' of peptides. GHK-Cu signals the body to repair damaged tissue, produce collagen and elastin, and even reverse the gene expression of old cells to a more youthful state. It is as effective on the skin as it is on the health of the internal organs and lungs.

Why do you appear online so much
- It's loved in luxury cosmetics for reducing wrinkles and blemishes, but biohackers use it in injectable form for systemic recovery, hair growth and protection against cognitive decline.

How it is framed today (pragmatic view)
- 1) Evidence: Thousands of studies have documented its benefits since the 1970s. 2) Purpose: Advanced aesthetics, wound healing and lung/cognitive health. 3) Risk: Copper levels should be balanced with zinc if used long-term.

How to use this form
- Explore the 'Genetic Studies' section to see how GHK-Cu affects the expression of survival genes.

- Quick profile (curated by Subject 157)
- Class: Other
- Status: Verified
- Use case: Other
- Route: Topical
- Tags: Topical|Injectable|Skin|Hair
- Half-life: ~1 Hour
- Start: Slow (Skin)
- Duration: Variable

- Mechanism (high level)
Tripeptide with a high affinity for copper (Cu2+). Modulates gene expression (genetic reset), increases collagen/elastin and repairs DNA damage.

- Evidence (what the literature covers)
RESEARCH RANGE (Cosmetic/Injectable, Non-prescriptive):
Topical (1-3%). Injectable (low doses, beware of copper toxicity).
Level of Evidence: A (Cosmetics).

- Safety and harm-reduction (non-prescriptive)
Risks: Local pain on injection.
Copper accumulation (monitor ZInco).
Interactions: Zinc (Competition).

- References (anchors)
- Pickart, L. (2008) - The human tri-peptide GHK and tissue remodelling - https://doi.org/10.1163/156856208784909435 | PubMed:18638426
- Arul, V. (2012) - GHK-Cu accelerates burn wound healing - https://doi.org/10.1155/2012/324832 | PubMed:23320042

Note: Educational/research content. Does not constitute medical advice, diagnosis or prescription.

Scientific References
Pickart, L. (2008) - The human tri-peptide GHK and tissue remodelling -
Arul, V. (2012) - GHK-Cu accelerates burn wound healing -
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Insulin Units (IU)
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LAB TOOLS
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Snapshot
Use CaseOther
AliasesCopper Peptide
StorageAmbient Temperature (Creams) / Frig (Inj).
HandlingIntense blue.
Interactions
Zinc (Competition).
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