Melanotan 2

What it is (in plain language)
- MT-2 does two main things: it stimulates melanin production (tanning) without the need for intense sun exposure and it acts on the central nervous system to significantly increase libido. It mimics the body's natural signal to 'darken' the skin and 'activate' sexual desire.

Why do you appear online so much
- It is extremely popular for its ability to provide a deep tan and for its effectiveness in treating erectile dysfunction and low libido. However, it is also one of the peptides that requires the most caution due to its systemic effects.

How it is framed today (pragmatic view)
- 1) Evidence: Widespread historical use, although not approved by the FDA for tanning. 2) Purpose: Aesthetics (pigmentation) and sexual health. 3) Risk: Can cause intense nausea, darkening of moles (nevi) and prolonged erections.

How to use this form
- Carefully read the warnings about monitoring moles and freckles in the risks section.

- Quick profile (curated by Subject 157)
- Class: Other
- Status: Verified
- Use case: Other
- Route: Injectable
- Tags: Injectable|Tanning|Libido
- Half-life: ~1 Hour
- Start: 30min - 2h
- Duration: Days (Tan)

- Mechanism (high level)
Non-selective agonist of melanocortin receptors (MC1R, MC3R, MC4R, MC5R). Stimulates melanogenesis (tanning) and central sexual arousal.

- Evidence (what the literature covers)
RESEARCH RANGE (Non-prescriptive):
Very low doses (50mcg-100mcg) to start with.
Level of Evidence: B.

- Safety and harm-reduction (non-prescriptive)
Risks: Severe nausea, flushing, priapism (attention), darkening of moles.
Interactions: Naltrexone.

- References (anchors)
- Dorr, R. T. (1996) - Melanotan-II synthetic analogue of alpha-MSH - https://doi.org/10.1016/0024-3205(96)00160-9 | PubMed:8667634
- Hadley, M. E. (2005) - Melanotan-II clinical results summary - https://doi.org/10.1016/j.peptides.2005.01.023 | PubMed:15862168

Note: Educational/research content. Does not constitute medical advice, diagnosis or prescription.