GHRP-2
Selective ghrelin receptor agonist (GHS-R1a). Stimulates strong pulses of GH directly in the pituitary. Slightly increases ACTH and Prolactin.
- Powerful GH pulses (post-workout/night)
- Increased appetite (moderate)
- Accelerated recovery
- Systemic anti-inflammatory effectPotent GH pulses (post-workout/evening)
- Systemic anti-inflammatory effect
- Increase in Cortisol and Prolactin (dose sensitive).
- Hunger (may be unwanted).
- Water retention.Increase in Cortisol and Prolactin (dose sensitive).
- Water retention.
GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide and a potent agonist of the growth hormone secretagogue receptor (GHS-R), acting directly on the pituitary gland and hypothalamus.
READ MORE
What it is (in plain language)
- It's a 'messenger' that orders your master gland (the pituitary gland) to release more Growth Hormone (GH). Unlike other versions, GHRP-2 is considered one of the most powerful stimulators, producing significant peaks of GH in short periods of time, which helps with muscle recovery and fat burning.
Why do you appear online so much
- It is one of the pillars of biohacking for physical performance. It's favoured by those looking for fast results in terms of lean mass and recovery, and is a balance between GHRP-6 (which causes a lot of hunger) and Ipamorelin (which is milder).
How it is framed today (pragmatic view)
- 1) Evidence: Widely documented in clinical endocrinology studies. 2) Purpose: Increase in lean mass and bone density. 3) Risk: May cause small increases in prolactin and cortisol levels, requiring hormonal monitoring if used for long periods.
How to use this form
- Check out the 'Interactions' section to find out how to avoid insulin spikes that can interfere with the peptide's effectiveness.
- Quick profile (curated by Subject 157)
- Class: Hormonal
- Status: Verified
- Use case: Muscle Growth
- Route: Injectable
- Tags: Injectable|GH|Bulking
- Half-life: ~30 Mins
- Start: Quick (15 min)
- Duration: ~2-3 hours
- Mechanism (high level)
Selective ghrelin receptor agonist (GHS-R1a). Stimulates strong pulses of GH directly in the pituitary. Slightly increases ACTH and Prolactin.
- Evidence (what the literature covers)
RESEARCH RANGE (Bodybuilding, Non-prescriptive):
Doses of 100mcg to 300mcg (1-3x day).
Level of Evidence: B.
- Safety and harm-reduction (non-prescriptive)
Risks: Increase in Cortisol and Prolactin (dose-sensitive).
Hunger (may be unwanted).
Water retention.
Interactions: Sugar (blunts effect).
- References (anchors)
- Laferrère, B. (2005) - GHRP-2 increases food intake in humans - https://doi.org/10.1210/jc.2004-1719 | PubMed:15637233
- Bowers, C. Y. (1992) - GHRP-2 and GH release in clinical studies - https://doi.org/10.1210/edrv-13-2-301 | PubMed:1607849
Note: Educational/research content. Does not constitute medical advice, diagnosis or prescription.
